Prolozone Therapy

BOOK YOUR FREE CONSULTATION
Call to Book
Illustration of a blue molecular structure representing the chemical formula for ozone, O3. Advertising prolozone injections at leigh injection clinic

Prolozone Therapy is an advanced, non-surgical approach designed to help people dealing with chronic pain and musculoskeletal conditions. It merges elements of ozone therapy and prolotherapy to encourage healing and improve the function of damaged tissues.

Difference Between Prolozone and Prolotherapy

Prolotherapy involves injecting a solution—commonly one based on dextrose—into weakened or injured ligaments, tendons, or joints. This irritant stimulates a mild inflammatory response, which activates the body’s natural healing process and helps repair and strengthen the affected areas.

Prolozone therapy builds on this concept by adding ozone to the injected solution. Ozone, a reactive form of oxygen, enhances the treatment by boosting oxygen supply, reducing inflammation, and promoting more efficient tissue repair compared to prolotherapy alone.

How It Works and Supports Tissue Health

Prolozone therapy aids healing through several key mechanisms:

  • Enhanced Oxygen Supply: Ozone increases oxygen delivery to the targeted area, improving cellular activity and supporting tissue repair. Oxygen is essential for energy production and collagen formation.

  • Reduced Inflammation: Ozone’s anti-inflammatory properties help decrease swelling, pain, and irritation, making the healing process more comfortable.

  • Tissue Regeneration: The combined effects of prolotherapy and ozone stimulate the body’s repair systems, leading to the development of new collagen and connective tissue. This strengthens ligaments and tendons while improving joint stability and function.

Conditions It May Help Treat

Prolozone therapy may be useful for various musculoskeletal issues, including:

  • Osteoarthritis

  • Tendinitis

  • Bursitis

  • Ligament injuries (sprains or tears)

  • Joint instability

  • Chronic back pain

  • Sports-related injuries

  • Degenerative joint conditions

What to Expect During Treatment

  • Initial Assessment: A healthcare provider reviews your medical history and performs a physical exam to determine if the therapy is appropriate.

  • Preparation: The treatment site is cleaned and sterilized to prevent infection.

  • Injection Process: A fine needle is used to inject a mixture of prolotherapy solution and ozone into the targeted area. Musculoskeletal injections are often guided by ultrasound for precision, while spinal injections rely on anatomical landmarks.

  • Aftercare: Mild soreness or swelling may occur following the procedure. Ice, rest, and over-the-counter medications are typically recommended to ease discomfort.

  • Follow-Up Sessions: Most patients require around 3–6 sessions, usually spaced two weeks apart, depending on their condition and response to treatment. Progress is monitored and adjustments are made as needed.

Summary

Prolozone therapy is a promising option for those seeking relief from chronic pain and musculoskeletal problems. By combining the benefits of ozone therapy with prolotherapy, it supports tissue healing, reduces inflammation, and helps restore proper function to joints, ligaments, and tendons.

3D illustration of ozone molecule with three connected spheres containing blue cloud-like textures, molecular structure in the background, and the chemical formula O3. Highlighting the structure of ozone, advertising prolozone therapy.

Reviews

  • "The prolozone treatment has been life changing for both myself and my partner. A life long agony of back pain as well as other issues has been relieved with a new lease of life. Truly, truly professional and friendly staff always caring and knowledgable. Thank you x"

    Gemma

  • "Excellent practice. Attended recently for Prolozone injections to help relieve pain from a bulging disc. After weeks of discomfort and restricted movement the treatment gave me relief and the ability to get back to normal. Cannot recommend highly enough."

    Julie

  • "Fantastic! Highly recommended. I have been struggling with lower back pain in my sciatic joints I had two prolozone treatments with Jon and feel all the pain has gone it even helped my ibs which was a bonus!"

PERSONALISED INJECTION THERAPY

Reduce your symptoms. Move pain-free. Let our team of experts guide you back to health.

Book a free consultation

Frequently Asked Questions

  • Prolozone® Therapy is a regenerative injection treatment designed to support the body's natural healing processes. The procedure combines therapeutic nutrients with medical oxygen - ozone gas, which are delivered directly into injured or painful tissues. By enhancing oxygen delivery, circulation and cellular function, Prolozone aims to reduce pain and encourage tissue repair without relying on steroids or surgery.

  • Prolozone may be beneficial for a wide range of musculoskeletal conditions, including:

    • Back pain and neck pain

    • Sciatica and nerve-related discomfort

    • Osteoarthritis and degenerative joint disease

    • Hip, knee and shoulder pain

    • Tendon and ligament injuries

    • Sports-related injuries

    • Plantar fasciitis

    • Chronic inflammation and soft tissue pain

    At the St Albans Injection Clinic, Prolozone is often chosen by patients looking for a non-surgical solution to persistent pain and reduced mobility.

  • Yes. Prolozone is frequently used to treat a variety of spinal pain conditions, including chronic neck pain, lower back pain and sciatica. Unlike steroid-based approaches that focus on temporary symptom relief, Prolozone is used to support tissue repair and address underlying dysfunction within the affected structures.

  • No. Prolozone injections are not performed under ultrasound guidance. The treatment targets specific ligament attachments, tendon insertions and supportive structures that are identified through detailed clinical assessment and precise anatomical techniques.

  • Prolozone works by supporting the body's natural repair mechanisms. Potential benefits include:

    • Increased oxygen delivery to damaged tissues

    • Improved cellular energy production

    • Reduced inflammation within injured structures

    • Enhanced tissue regeneration and recovery

    • Support for stronger ligaments, tendons and connective tissues

    This regenerative approach aims to encourage longer-term healing rather than simply masking symptoms.

  • The number of sessions varies according to the condition being treated and its severity. Most patients undergo a course of between three and six treatments. Some individuals notice improvements after their first session, while others experience more gradual progress over several appointments.

  • Patients commonly report:

    • Reduced pain levels

    • Improved flexibility and range of motion

    • Better joint function and stability

    • Increased ability to exercise and remain active

    • Long-term improvements in mobility and quality of life

    As with all regenerative treatments, results can vary depending on the individual and the condition being treated.

  • Prolozone is generally considered a safe procedure when performed by an experienced clinician. Side effects are usually mild and temporary, with some patients experiencing short-lived soreness, stiffness or tenderness around the treatment area following the injection.

  • See Table 1 below.

  • You may be a good candidate for Prolozone if you:

    • Have ongoing pain that has not improved with conventional treatment

    • Suffer from osteoarthritis, joint degeneration or instability

    • Have tendon, ligament or soft tissue injuries

    • Wish to avoid steroid injections, surgery or long-term pain medication

    • Are looking for a regenerative treatment option to support recovery

    A consultation at the St Albans Injection Clinic will help determine whether Prolozone® Therapy is appropriate for your condition and treatment goals.

Resources

Prolozone Therapy Steroid / Cortisone Injections
Supports regenerative healing Anti-inflammatory only
Supports repair & strengthens tissues Does not repair damage
Long-term improvement Short-term relief
Suitable for spinal pain Not used in spine at our clinic

Table 1: Prolozone Therapy vs. Steroid Injections